Micheal Siani drove in four runs to power the St. Louis Cardinals past the visiting Baltimore Orioles 6-3 Monday night.

Siani hit his first career homer, a three-run shot, and an RBI single as the Cardinals won for the sixth time in eight games.

Masyn Winn drove in two runs for St. Louis while extending his hitting streak to 11 games with a double and a single.

Cardinals starting pitcher Sonny Gray (6-2) allowed three runs (one earned) on three hits in 5 2/3 innings. He struck out six and walked two.

Relievers JoJo Romero, John King, Andrew Kittredge and Ryan Helsley took it from there — with Helsley earning his 14th save.

Gunnar Henderson hit a three-run home run for the Orioles, running his homer streak to four games.

Orioles starting pitcher Dean Kremer (3-4) allowed five runs on six hits and three walks in four innings. He struck out two.

The Cardinals took a 1-0 lead in the second inning when Nolan Gorman walked with one out, stole second base and scored on Siani’s two-out single.

St. Louis increased its lead to 5-0 in the fourth inning. Alec Burleson led off the inning with a single and went to third on Ivan Herrera’s single. Winn hit a one-out RBI double, then Siani smacked his homer.

The Orioles capitalized on two Winn errors to cut their deficit to 5-3 in the sixth inning. Winn dropped Cedric Mullins’ popup into shallow left field leading off the inning, then one batter later he failed to field Jorge Mateo’s grounder.

Henderson made the Cardinals pay for those mistakes with a three-run homer.

Ryan O’Hearn and Jordan Westburg his one-out singles later in the inning, but Gray retired Anthony Santander on a flyout and Romero got Ryan Mountcastle to hit an inning-ending groundout.

The Cardinals increased their lead to 6-3 in the seventh inning. Paul Goldschmidt walked to lead off the inning. One out later, Burleson hit a single and Herrera walked before Winn hit a two-out RBI infield single.